Laboratoire Léon Brillouin

UMR12 CEA-CNRS, Bât. 563 CEA Saclay

91191 Gif sur Yvette Cedex, France

+33-169085241 llb-sec@cea.fr

BD diffusons les neutrons

07 avril 2024
Nina Královič-Kanjaková, Ali Asi Shirazi, Lukáš Hubčík, Mária Klacsová, Atoosa Keshavarzi, Juan Carlos Martínez, Sophie Combet, José Teixeira, and Daniela Uhríková The use of an exogenous pulmonary surfactant (EPS) to deliver other relevant drugs to the lungs is a promising strategy for combined therapy.
16 février 2024
On De Gennes narrowing of fluids confined at the molecular scale in nanoporous materials Wanda Kellouai, Jean-Louis Barrat, Patrick Judeinstein, Marie Plazanet, Benoit Coasne, J.
01 décembre 2023
Anne-Charlotte Le Gulluche, Guylaine Ducouret, Ludovic Olanier, Annie Brûlet, Olivier Sanseau, Paul Sotta, and Alba Marcellan Model hybrid hydrogels reinforced by silica nanoparticles were designed by polymerizing and cross-linking the gels in situ.
13 octobre 2023
Antoine Cossa, Sylvain Trépout, Frank Wien, Johannes Groen, Etienne Le Brun, Florian Turbant, Laetitia Besse, Eva Pereiro, Véronique Arluison The bacterial chromosomic DNA is packed within a membrane-less structure, the nucleoid, due to the association of DNA with proteins called Nucleoid Associated Proteins (NAPs).
25 août 2023
Maëva Almeida, Daniel Dudzinski, Catherine Amiel, Jean-Michel Guigner,Sylvain Prévost, Clémence Le Coeur and Fabrice Cousin Here, we describe the behavior of mixtures of stearic acid (SA) and its hydroxylated counterpart 12-hydroxystearic acid (12-HSA) in aqueous mixtures at room temperature as a function of the 12-HSA/SA mole ratio R.
06 juillet 2023
Simeon Minic, Burkhard Annighöfer, Milos Milcic, François Maignen, Annie Brûlet, Sophie Combet Apomyoglobin (apoMb), a model protein in biochemistry, exhibits a strong propensity to bind various ligands, which makes it a good candidate as a carrier of bioactive hydrophobic drugs.
13 juin 2023
Somia Haouache, Yu Chen, Clara Jimenez-Saelices, Fabrice Cousin, Pan Chen, Yoshiharu Nishiyama, François Jerome, and Isabelle Capron Nanocelluloses can be used to stabilize oil–water surfaces, forming so-called Pickering emulsions.
02 mai 2023
Céline JAUDOIN, Isabelle GRILLO, Fabrice COUSIN, Maria GEHRKE, Malika OULDALI, Ana-Andreea ARTENI, Luc PICTON, Christophe RIHOUEY, Fanny SIMELIERE, Amélie BOCHOT, Florence AGNELY Mixtures of hyaluronic acid (HA) with liposomes lead to hybrid colloid–polymer systems with a great interest in drug delivery.
08 avril 2023
Anne-Sophie Robbes, Jacques Jestin, Florian Meneau, Florent Dalmas, François Boué, and Fabrice Cousin, Macromolecules 2022, 55, 15, 6876–6889.
14 mars 2023
Michal Swierczewski,  Fabrice Cousin,  Ewa Banach,  Arnulf Rosspeintner,  Latevi Max Lawson Daku,  Abolfazl Ziarati,  Rania Kazan,  Gunnar Jeschke,  Raymond Azoulay,  Lay-Theng Lee,  Thomas Bürgi A bidentate chiral dithiol (diBINAS) is utilised to bridge Au25 nanoclusters to form oligomers.
19 février 2023
Florian Turbant, Jehan Waeytens, Camille Campidelli, Marianne Bombled, Denis Martinez, Axelle Grélard, Birgit Habenstein, Vincent Raussens, Marisela Velez, Frank Wien, Véronique Arluison Hfq is a pleiotropic regulator that mediates several aspects of bacterial RNA metabolism.
27 janvier 2023
Sophie Combet, Françoise Bonneté, Stéphanie Finet, Alexandre Pozza, Christelle Saade, Anne Martel, Alexandros Koutsioubas, Jean-Jacques Lacapère, Biochimie (2022) in press.
28 novembre 2022
H. P. Khanh Ngo, E. Planes, C. Iojoiu, P. Soudant, A.-L. Rollet, P.
07 novembre 2022
Michal Swierczewski, Alexis Chenneviere, Lay-Theng Lee, Plinio Maroni, Thomas Bürgi Langmuir-Blodgett (LB) technique allows the deposition of gold nanoclusters (atomically precise nanoparticles below 2 nm in diameter) onto solid substrates with an unprecedented degree of control and high transfer ratios.
02 septembre 2022
Simeon Minić, Burkhard Annighöfer, Arnaud Hélary, Laïla Sago, David Cornu, Annie Brûlet, Sophie Combet High pressure (HP) is a particularly powerful tool to study protein folding/unfolding, revealing subtle structural rearrangements.
01 juillet 2022
Tiago Outerelo Corvo, Antoine Jourdain, Shona O’Brien, Frédéric Restagno, Eric Drockenmuller, and Alexis Chennevière Poly(ionic liquid)s (PILs), similar to their ionic liquid (IL) analogues, present a nanostructure arising from local interactions.
02 juin 2022
Marion Grzelka, Iurii Antoniuk, Éric Drockenmuller, Alexis Chennevière, Liliane Léger, and Frédéric Restagno The role of the polymer volume fraction, ϕ, on steady-state slippage and interfacial friction is investigated for semi-dilute polystyrene solutions in diethyl phthalate in contact with two solid surfaces.
21 avril 2022
Sumit Mehan, Laure Herrmann, Jean-Paul Chapel, Jacques Jestin, Jean-Francois Berret and Fabrice Cousin We investigate the formation/re-dissociation mechanisms of hybrid complexes made from negatively charged PAA2k coated g-Fe2O3 nanoparticles (NP) and positively charged polycations (PDADMAC) in aqueous solution in the regime of very high ionic strength (I).
23 mars 2022
Christiane Alba-Simionesco , Patrick Judeinstein , Stéphane Longeville, Oriana Osta , Florence Porcher , Frédéric Caupin , and Gilles Tarjus The proneness of water to crystallize is a major obstacle to understanding its putative exotic behavior in the supercooled state.
22 février 2022
J.C.Riedl, M.Sarkar, T.Fiuza, F.Cousin, J.Depeyrot, E.Dubois,G.Mériguet,R.Perzynski and V.
15 décembre 2021
Virginie Vergnat, Benoît Heinrich, Michel Rawiso, René Muller, Geneviève Pourroy and Patrick Masson Embedding nanoparticles (NPs) with organic shells is a way to control their aggregation behavior.
02 novembre 2021
Michal Swierczewski, Plinio Maroni, Alexis Chenneviere, Mohammad M.
10 octobre 2021
J. Wolanin, L. Michel, D. Tabacchioni, J. M. Zanotti, J. Peters, I. Imaz, B. Coasne, M. Plazanet, and C.
18 septembre 2021
T. Fiuza, M. Sarkar, J. C. Riedl, A. Cebers, F. Cousin, G. Demouchy, J. Depeyrot, E. Dubois, F. Gelebart, G. Meriguet, R. Perzynski and V.
27 août 2021
Eni Kume and Laurence Noirez In the conventional picture, the temperature of a liquid bath in the quiescent state is uniform down to thermal fluctuation length scales.
12 avril 2021
Julie Wolanin, Jérôme Giraud, Claude Payre, Marianne Benoit, Claire Antonelli, Damien Quemener, Iliass Tahiri, Matthieu Vandamme, Jean-Marc Zanotti, and Marie Plazanet, Review of Scientific Instruments 92 (2021) 024106 In comparison to condensed matter, soft matter is subject to several interplaying effects (surface heterogeneities and swelling effect) that influence transport at the nanoscale.
05 avril 2021
In the Léon Brillouin Laboratory (LLB), and for the community of neutron scattering, this month of March 2021 was marked by an important event: the first neutron beam of the SHARP* instrument, a new time-of-flight neutron spectrometer, at the European reactor of the Institut Laue Langevin (ILL) in Grenoble.
23 décembre 2020
Liu Chang; Hu Wenxian; Jiang Hanqiu; Liu Guoming; Han Charles; Sirringhaus Henning; Boué François; Wang Dujin The determination of intrinsic chain stiffness of conjugated polymers is challenging, in particular, for scattering techniques because of their strong light absorption and structural instability due to the complicated intra-/intermolecular interactions.
02 décembre 2020
Simeon Minic, Burkhard Annighofer, Arnaud Helary, Djemel Hamdane, Gaston Hui Bon Hoa, Camille Loupiac, Annie Brulet, and Sophie Combet To probe intermediate states during unfolding and oligomerization of proteins remains a major challenge.

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